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CAS NO.103-90-2
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Use name acetaminophen
English name 4-Acetamidophenol
CAS No. 103-90-2
Molecular Weight 151.163
Use of acetaminophen
Acetaminophen (paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with IC50 of 25.8 μM. It is a widely used antipyretic and pain reliever.
Acetaminophen effect
This product is an antipyretic analgesic. It inhibits cyclooxygenase and selectively inhibits the synthesis of prostaglandins in the hypothalamus thermoregulatory center, resulting in peripheral vasodilation and sweating to achieve antipyretic effect. Its antipyretic effect is similar to aspirin. Similar; by inhibiting the synthesis and release of prostaglandins, etc., and increasing the pain threshold, it has an analgesic effect. It is a peripheral analgesic, and its effect is weaker than that of aspirin. It is only effective for mild and moderate pain. This product has no obvious anti-inflammatory effect.
Density 1.3±0.1 g/cm3
Boiling point 387.8±25.0 °C at 760 mmHg
Melting point 168-172 °C(lit.)
Molecular formula C8H9NO2
Molecular weight 151.163
Flash point 188.4±23.2 °C
Exact mass 151.063324
PSA 49.33000
LogP 0.34
Vapor Pressure 0.0±0.9 mmHg at 25°C
Refractive index 1.619
Storage conditions 1. Store in a cool, ventilated warehouse. Keep away from fire and heat sources. Keep container tightly closed. should be kept away from oxidizer, do not store together. Equipped with the appropriate variety and quantity of fire equipment. Storage areas should be provided with suitable materials to contain spills.
stability
1. Avoid contact with oxides.
2. Toxic and irritating, avoid contact with eyes and skin when using.
Water solubility 14 g/L (20 ºC)